The chemical modification methods of food proteins are summarized,including acylation,deamidation,phosphorylation,glycosylation,covalent cross-linking effect etc.
Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.
The title resin has been prepared by Friedel-Crafts acylation followed by bromination and amination.The method avoids the utilization of cancerogenic chloromethyl methyl ether.