Objective:To study the antifungal activity of triazole alcohols by introduction of cyclopropyl as side chain.
研究具有环丙基结构的三唑醇物的抗真菌活性。
Here, we show that deletions of VPS28 and VPS32 increase the susceptibility of C. albicans to cell wall disruption agents, echinocandin and azole antifungal agents.
【文献摘要】Vps28p and Vps32p act in both the endocytic and the pH signaling pathways in yeasts and are required for Candida albicans virulence.
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