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Despite advances in the diagnosis and treatment of the antineutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitides, renal morbidity is common.

虽然对于抗中粒细胞胞浆抗(ANCA)相治疗有较大的进展,但是肾脏的损害依然很严重。

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Osmosis-神经

In addition, plasmapheresis can be effective as well, which is when the plasma is filtered to remove disease-causing autoantibodies.

另外,血浆置换也有效果,通过过滤血浆移除导致疾病的自身抗体。

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Osmosis-肌骨

But unlike many other autoimmune conditions, no autoantibody has been specifically linked to the disease.

和其他的自身免疫病不同,至今尚未发现和该病特异性相关的自身抗体。

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Osmosis-泌尿

One way these complexes can form is as a result of autoantibodies directly targeting the glomerular basement membrane.

合物形成的途径之一是自身抗体接攻击肾小球基膜。

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This condition is actually an autoimmune disease in which autoantibodies target natively produced proteins, some of which are secreted by cartilage cells.

情况实际是自身免疫性疾病,自身抗体靶向正常产生的蛋白质,有蛋白质是软骨细胞分泌的。

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Osmosis-肌骨

Spondyloarthropathies are all autoimmune diseases that affect the joints, and they're seronegative, which refers to the fact that rheumatoid factor, which is an autoantibody, is not found in the blood.

脊柱关节病是一类累及关节、且血清学呈阴性的自身免疫病;血清学阴性是指患者血液中未发现类风湿因子自身抗体。

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Osmosis-泌尿

The rest of cases, though, are secondary, and seem to arise from autoantibodies that are generated in response to another process like an infection, malignancies, autoimmune conditions, or medications.

另一病因是继发性的,自身抗体来源于对机体其他疾病的应答,如感染,恶性肿瘤,自身免疫状态或药物等。

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Osmosis-神经

In very rare cases, myasthenia gravis can present as a paraneoplastic syndrome, which means that an underlying cancer like bronchogenic carcinoma or thymic neoplasm (also known as thymoma) generates an immune response which results in generation of autoantibodies.

在极罕见的情况下,重症肌无力会表现出副肿瘤综合征,意味着潜在的癌症如支气管肺癌、胸腺肿瘤导致免疫应答产生了自身抗体。

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