Similar to the party pooper is a Debbie downer.

“令人扫兴的人”类似的还有“Debbie downer”。

Oh, God. I shouldn't be here. -Come on. Don't be a downer.

天啊。我不该来这儿。-拜托，别那么扫兴。

A person who always has a stick-in-the-mud attitude could also be called a downer.

一个总是墨守成规的人也可以被称为扫兴者。

I don't want to be a downer here, but life on Earth has

也许不是明天，但我们快没时间了。

In some situations, using downers can lead to death.

在一些情况下，便用镇静剂可导致死亡。

I mean it is a downer-much like alcohol itself.

这真让人郁闷，就像酒精本身一样。

Downers are known to cause headaches, feelings of sadness and a weak pulse.

镇静剂悉可以引起头痛，伤感虚弱。

A person who always has a stick-in-the-mud attitude could also be called a downer. This means they bring people down.

一个总是墨守成规的人也可以被称为" downer" （扫兴的人）。这意味着他们总会让气氛冷场。

You know, if you're on a downer, if you will, sometimes your body just responds accordingly.

你知道，如果你情绪低落，如果你愿意，有时你的身体会做出相应的反应。

Do you have another downer for us?

您还有其他让我们沮丧的事情吗？

Not to be a downer but it just doesn't seem practical within the limited time frame given by 2050.

不是让人沮丧，但在到 2050 年的有限时间内，这似乎并不现实。

Most of epigenetic research has really focused on stress, anxiety, depression -- kind of a downer, kind of bad things.

大多数的表观遗传学研究都集中在压力，焦虑，抑郁上—某种负面情绪，某种不好的事情。

Some of these are like downers and I'm totally willing to admit that, but this is an absolute dance song.

其中有些会让人感到很沮丧，但这首歌绝对是一首舞蹈佳曲。

And the researchers found that just the act of scheduling an activity actually put kind of a downer on things.

研究人员发现，仅仅是安排活动的行为，就能让事情变得有点沮丧。

No. No. I'm not eating with those downers!

不，不。我不才不跟 那帮晦气吃饭！

Well, before you pause to go get the snack, sorry to put a downer on your appetite, but food really can be dangerous.

好吧，在你停下这个视频去拿零食之前——很抱歉我让你食欲不振了——但食物真的很危险。

He simply stated that most of the news was bad news, and he added, " It's kind of a downer." He had me.

他只说绝大多数新闻都是负面消息，然后加了一句，“有点让人沮丧。”这番话一时把我问住了。

I'm- I'm making it all about me. What a downer. It's your evening. Let's make it great, man. - No. No.

我把自己弄成主角了。真是扫兴。今晚的主角是你。让今夜此生难忘吧。-没没。

Or do you want to be the nit-picker, downer, who thinks everything is not so good?

或者你想成为吹毛求疵、情绪低落的人，认为一切都不太好？

And so this is not just a downer about how to stop things from getting worse, but also a chance to make things better.

所以这并不是只能阻止坏情况发酵的灰心事，而是一个让世界变更好的机会。