If fertilization doesn't happen, then the corpus luteum stops making hormones after around 10 days, becomes fibrotic, and is called the corpus albicans.
If fertilization doesn't happen, then the corpus luteum stops making hormones after approximately 10 days, becomes fibrotic, and is called the corpus albicans.
As part of the subsequent healing process pancreatic stellate cells lay down fibrotic tissue which causes narrowing, or stenosis of the ducts, as well as acinar cell atrophy.
The fibrotic tissue, pressure buildup, and diversion of blood from the hepatic circulation essentially reduces the number of functional sinusoidal veins, and the number of functional portal triads in general.
In the short term, there is muscle regeneration resulting in muscle fibers of different sizes, but in the long term, the muscles atrophy and are infiltrated by fat and fibrotic tissue, which leaves them really weak.