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So in fibrotic livers you can find cannabinoid receptors that have both anti- and pro-fibrogenic effects.

的肝脏麻素受体既有抗作用也有促作用。

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Osmosis-消化

How do these bands of fibrotic tissue form though?

那么这些纤维束又是如何形成的呢?

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Osmosis-消化

As this fibrotic tissue builds up, it starts to compress the central veins and sinusoids.

堆积在一起的纤维组织会挤压中和血窦。

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Osmosis-消化

Most commonly, this happens because of hepatic cirrhosis, which is when the liver tissue is replaced by fibrotic functionless tissue.

它大多数由肝硬化引起,即肝脏组织被无功能的纤维组织替代。

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Osmosis-解剖与生理

If fertilization doesn't happen, then the corpus luteum stops making hormones after around 10 days, becomes fibrotic, and is called the corpus albicans.

如果次级卵母细胞没有受精,大概10天之后,黄体就会停释放激素而纤维化,形成白体。

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Osmosis-生殖

If fertilization doesn't happen, then the corpus luteum stops making hormones after approximately 10 days, becomes fibrotic, and is called the corpus albicans.

如果未受精,黄体会在大概10天后停生成激素,并纤维化变成白体。

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Osmosis-消化

Also with cirrhotic liver tissue, you'll see that in between these clumps of cells or nodules, is fibrotic tissue and collagen.

在纤维化的肝脏组织里,成堆的细胞之间,还有纤维组织和胶原的存在。

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Osmosis-消化

Alright, as a quick recap, cirrhosis is when inflammation and liver damage causes the liver to become fibrotic and develop scar tissue.

得!快速总一下:肝硬化是指由炎症和肝脏损伤导致肝脏纤维化,并形成瘢痕组织。

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Osmosis-消化

As part of the subsequent healing process pancreatic stellate cells lay down fibrotic tissue which causes narrowing, or stenosis of the ducts, as well as acinar cell atrophy.

作为后续修复愈合过程的一部分,胰腺星状细胞会产生纤维化组织,造成导管狭窄及腺泡细胞萎缩。

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Osmosis-消化

If we zoom out a bit and look at it with the naked eye, we'll again see these nodules, which have fibrotic protein bands in between.

如果我们直接通过肉眼直接观察肝脏,我们仍会看到这些以及填充在他们之间的纤维化蛋白质束。

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Osmosis-消化

The fibrotic tissue, pressure buildup, and diversion of blood from the hepatic circulation essentially reduces the number of functional sinusoidal veins, and the number of functional portal triads in general.

纤维组织形成、门高压和肝循环血液分流,最终导致了可用的血窦数量的减少,以及整体上可用的门三联管数量减少。

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Osmosis-肌骨

In the short term, there is muscle regeneration resulting in muscle fibers of different sizes, but in the long term, the muscles atrophy and are infiltrated by fat and fibrotic tissue, which leaves them really weak.

短期内,肌肉再生造成大小参差的肌纤维细胞,但是长期下去,肌肉萎缩并且脂肪组织和缔纤维组织增生渗入其间,导致肌肉无力。

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