The majority of cells in the human brain are not nerve cells but star-shaped glia cells, the so called “astroglia”.
人大部分细胞并神经细胞,而是质细胞。
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In fact, there are probably almost as many glia in your brain and nervous system as there are neurons!
事实上,你大脑和神系统中神胶质细胞可能几乎和神一样多!
In these studies, scientists transformed glia cells into neurons that had all the typical features you'd expect.
在这些研究中,科学家将神胶质细胞转化为具有你所期望所有典型神。
Glia surround neurons and, according to some scientists, may even outnumber them by as many as ten to one.
胶质细胞围绕神,一些科学家称,其数量比可能是十多个神胶质细胞对一个神。
Now, if glia are so important, it might seem unwise to transform some of them into neurons.
如果胶质细胞如此重要,那么将它们中一些转化为神似乎是不明智。
To name just one example, patterns of activity between neurons are likely influenced by a type of cell called glia.
仅举一个例子,神之间活动模式很可能受到一种称为神胶质细胞影响。
Defects in glia function are connected with aging in animals such as fruit flies and mice.
胶质细胞功能缺陷与果蝇和小鼠等动物衰老有关。
But luckily, new glia are reliably produced throughout adulthood, so swapping a few of them shouldn't pose a long-term problem.
但幸运是,新胶质细胞在整个成年期都能可靠地产生,因此更换其中一些不应构成长期问题。
In experiments on mice, they took a type of cell called a glia cell, and they transformed it into a neuron.
在对老鼠实验中,他们采用了一种称为神胶质细胞细胞,并将其转化为神。
In papers published that year, two research groups did just that by using AAV or CRISPR to make a simple genetic edit in glia cells.
在当年发表论文中,两个研究小组通过使用 AAV 或 CRISPR 在神胶质细胞中进行简单基因编辑来做到这一点。
And in their studies, scientists were able to convert glia into neurons by decreasing or knocking down the activity of just one small gene family called PTBP.
在他们研究中,科学家们能够通过减少或抑制一个名为 PTBP 小基因家族活动,将神胶质细胞转化为神。
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