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1.Testicular allotransplantation is one of the effective options for the treatment of male infertility and hypogonadism.

1.异体植是治疗男性不育或性腺减退的有效方法之一

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2.Methods 4 patients underwent testis homotransplantion with their relatives testis as donor tissue.Of them, 2 suffered from iatrogenic anorchia and the other 2 from hypogonadism.

2.方法利用亲属作供体行同种异体植4例,其中医源性无症2例,原发性性腺2例,术后观察患者血清酮水平、第二性征变化及性功情况

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Osmosis-

1.Some congenital causes of primary hypogonadism are genetic diseases like Klinefelter or Turner syndrome.

可引起原发性性腺功能减退的先天因包括Klinefelter综合征或Turner综合征等

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Osmosis-生殖

2.Next, endocrine dysfunctions that causes testosterone levels to fall, like hypogonadism, can cause erectile dysfunction.

其次,功能障碍导致睾酮水平下降,如性腺功能减退会导致勃起功能障碍。

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3.Some acquired causes of primary hypogonadism are radiation therapy, chemotherapy, and trauma to the gonads.

可引起原发性性腺功能减退症的获得性因有放疗、化疗和性腺创伤。

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4.These streak ovaries can't produce sex hormones, resulting in hypogonadism and low estrogen levels.

这些条索状卵巢无法产生性激,导致性腺功能低下、雌激水平低。

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Osmosis-

5.There are two main causes of hypogonadism.

性腺功能减退有两个主要

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6.Because of this, Kallmann syndrome is a type of hypogonadotropic hypogonadism disorder.

正因如此,Kallmann综合征是一种低促性腺激性性腺功能减退症。

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Osmosis-

7.Some acquired causes are similar to primary hypogonadism, radiation therapy, chemotherapy, and trauma to the gonads.

有些获得性因与原发性性腺功能减退症相似,也包括放疗、化疗和性腺创伤。

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Osmosis-

8.Blood tests of hormone levels can give an idea of the type of hypogonadism.

血液激水平的检测可以为性腺功能减退的类型提供参考

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9.So, to recap: Kallmann syndrome is a type of hypogonadotropic hypogonadism where olfactory neurons and gonadotropin-releasing hormone neurons don't function normally.

Kallmann综合征是一种低促性腺激性腺功能减退症,其嗅觉神经元与促性腺激释放激神经元不能发挥正常功能。

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Osmosis-

10.This leads to an overproduction of luteinizing and follicle stimulating hormones, so primary hypogonadism is also called hypergonadotropic hypogonadism.

这会导致LH和FSH生成过多,所以原发性性腺功能减退症也称为高促性腺激性性腺功能减退症。

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Osmosis-

11.This is called hypergonadotropic (because the level of gonadotropins are high) hypogonadism (because the level of gonad or ovarian hormones is low).

由于促性腺激水平高,而性腺或卵巢激水平低,这被称为高促性腺激型性腺功能减退症

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Osmosis-

12.Though there are different causes which result in different levels of gonadotropin hormones, they all ultimately result in hypogonadism and a deficiency in testosterone or estrogen and progesterone.

尽管青春期延迟的因很多,会导致促性腺激水平各不相同,但最终的结果都是性腺功能减退以及男性睾酮或女性雌激和孕酮的缺乏。

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Osmosis-

13.The second cause of hypogonadism is secondary hypogonadism, which is also called hypogonadotropic hypogonadism because there are low levels of luteinizing and follicle stimulating hormones.

性腺功能减退的第二个因是继发性性腺功能减退症,也称为低促性腺性性腺功能减退症,因为LH和FSH激水平在此中都显著降低。

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14.Just like in secondary hypogonadism, there's a lack of gonadotropin-releasing hormone, but the key difference is that it's not considered pathologic - instead, it's thought to be a naturally slowed rate of maturation.

与继发性性腺功能减退症类似也存在GnRH的缺乏,但关键的区别在于这种缺乏不是理性的,而是一种正常的发育延迟。

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15.Secondary hypogonadism can be due to hypothalamus or pituitary gland dysfunction; either from an inability to produce gonadotropin-releasing hormone or luteinizing and follicle stimulating hormones, or suppression from other hormones, like prolactin or thyroid hormone.

继发性性腺功能减退症可由下丘脑或垂体功能障碍导致,既可能是促性腺激释放激、黄体生成和卵泡刺激的生成能力低下,也可能是以上激受到了其他激的抑制,例如或甲状腺激

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Osmosis-

16.The first is primary hypogonadism which is caused by dysfunction of the gonads - for example, the gonad's receptors may not respond to gonadotropin hormones, or the gonads might not have healthy cells that are capable of producing hormone.

一是原发性性腺功能减退,由性腺功能障碍引起,例如,性腺受体对促性腺激不敏感或者性腺没有能够产生性激的健康细胞。

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