In the oral ammonia liquid group, secretion of histamine was reduced, and after regiving of gastrin and muscarine, the secretion of histamine remained in an inhibitory state.
Their work reveals that muscarine, another compound hallucinogenic to the mammalian brain, has been produced in the fruiting bodies of fungi for 60 million years.
Many species within this family have conserved the alleles required to synthesizing muscarine until the present day, with a smaller subset of living genera within this family to lose this trait.