In mice, widespread deletion of the tumor suppressor Phosphatase and tensin homolog (PTEN) generates hamartomatous intestinal polyps with epithelial and stromal inolement.
在小鼠,广泛肿瘤抑制因子磷酸酶和张蛋白同源物〔PTEN〕产生错构小,含有上皮和间质。
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MSCs differentiate into adipocytes, osteocytes, chondrocytes, tenocytes, marrow stromal cells, muscle, and perhaps neuronal cells and are being used in early clinical trials to enhance bone marrow grafting and to suppress graft-versus-host disease in allogeneic bone marrow transplants.
MSCs分化成脂肪,,软,肌腱,髓基质,肌肉和神经,并用于早期临床试验,以增强髓移植和抑制同种异体髓移植中移植物抗宿主病。