Hyperplasia of synovium leads to formation of pannus which destroys cartilage and bone in the affected joint.
大增生的滑膜组织会导致血管的生,进而逐渐侵蚀软骨,造的损伤。
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As " type A" cells in the synovium attempt to remove the debris, immune cells like lymphocytes and macrophages are recruited into the synovial membrane, which produces proinflammatory cytokines that ultimately cause inflammation of the synovium as well, called synovitis.
滑膜上的A型细清除这些碎片的同时,免疫细(如淋巴细、巨噬细)也被募集进入滑膜,产生炎症因子,最终导致滑膜炎。
The synovium's composed of loose connective tissue, blood vessels, lymphatic vessels, and on the surface—" Type A" cells that clear cellular debris and " Type B" cells that produce components of synovial fluid, which helps lubricate the two articular surfaces.
滑膜由松散结缔织、血管、淋巴管成;在滑膜表面,A型细清理细碎屑,B型细产生滑液成分,滑液能够润滑两块关节的表面。