Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明线粒脱氢酶是硝酸甘油生物转的主要途径,线粒脱氢酶同时具有脱氢酶和酯酶的活性,其酯酶活性可以通过将硝酸甘油脱硝形成一氧氮,进而血管扩张。