Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明线粒体乙醛脱酶是体内催化硝生物转化的主要途径,线粒体乙醛脱酶同时具有脱酶和酶的催化活,酶活可以通过将硝脱硝形成一氧化氮,进而血管扩张。