Method The target compound was synthesized from clarithromycin via hydrolyzation,acetylation,cyclic carbonatation,oxidation,decarbonatation,acylation,cyclic carbamatation and cyclization.

方法以克拉霉素为起始原料,经水解、乙、酯、氧、脱酯、、氨基甲酯和合等反应合成目标合物。